Squamous cell carcinoma from oral lichen planus: a case report of a lesion with 28 years of evolution
Da Silva Silveira Wanessa, Bottezini Ezequiel Gregolin, Linden Maria Salete, Rinaldi Isadora, Paranhos Luiz Renato, De Carli Joao Paulo, Trentin Micheline, Dos Santos Pamela Leticia,
소속 상세정보
( Da Silva Silveira Wanessa ) - University of Passo Fundo Department of Dentistry
( Bottezini Ezequiel Gregolin ) - University of Passo Fundo Department of Dentistry
( Linden Maria Salete ) - University of Passo Fundo Department of Dentistry
( Rinaldi Isadora ) - University of Passo Fundo Department of Dentistry
( Paranhos Luiz Renato ) - Federal University of Sergipe Department of Dentistry
( De Carli Joao Paulo ) - University of Passo Fundo Department of Dentistry
( Trentin Micheline ) - University of Passo Fundo Department of Dentistry
( Dos Santos Pamela Leticia ) - Sagrado Coracao University Department of Dentistry
Abstract
Lichen planus (LP) is a relatively common mucocutaneous disease with autoimmune etiology. Considering its malignancy potential, it is important to define the correct diagnosis, treatment, and clinical follow-up for patients with LP so that the disease is not diagnosed late, thus hindering the chances of curing the disease. This study aims to describe a clinical case of oral squamous cell carcinoma, potentially originated from LP. The patient is undergoing clinical and histopathological follow-up. A 64-year-old Caucasian male patient presented with a proliferative verrucous lesion on the tongue and sought treatment at the School of Dentistry, University of Passo Fundo (UPF), Passo Fundo, Brazil. He claimed the lesion had been present since 1988, and had been initially diagnoses as “oral lichen planus.” The physical exam presented three diagnostic hypotheses: plaque-like oral LP, verrucous carcinoma, and squamous cell carcinoma. After incisional biopsy and histopathological analysis, squamous cell carcinoma was diagnosed, probably originating from oral LP. The case study shows that malignancy from oral LP is possible, which justifies periodic clinical and histopathological follow-up, as well as the elimination of risk factors for carcinoma in patients with oral LP.
키워드
Squamous cell carcinoma; Oral lichen planus; Oral cancer; Mouth neoplasms
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